Enzymes are biological catalysts that lower the activation energy of chemical reactions, allowing them to proceed at a faster rate. This illustration depicts the process of enzyme catalysis. The ...
Young, L & Post, CB. (1996) Catalysis by entropic guidance from enzymes. Biochemistry (New Concepts article) 35: 15129-15133. doi: 10.1021/bi961875m Post, CB & Ray, WJ, Jr. (1995) Reexamination of ...
Figure 1: Active site structures of representative nonheme iron enzymes with a 2-His-1-carboxylate facial triad and the reactions they catalyze. A comparison of the primary sequence information of ...
This evolutionary course is in striking contrast to the observation that the reactions catalyzed by many superfamilies of distantly related enzymes share at least a common partial reaction.
However, it is safe to say that no enzyme is perfect in the sense of catalyzing only a single reaction with a single substrate. For enzymes such as P450s and glutathione S-transferases that are ...
“In all cases, newly generated enzyme variants demonstrated improved amide bond formation. Taken together, our work highlights both the versatility of McbA to be directed to catalyze many unique ...