In a new role for an ion transporter, Na +-K +-Cl − cotransporter-1 may regulate the lung endothelial and epithelial barriers and consequently modulate the host response to pneumonia and sepsis.

As the body’s first line of defense against microbial intruders, epithelial cells are known for their ability to form tight physical and chemical barriers in tissues. But just how they maintain these ...

A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — ...

The CRB1 gene encodes a transmembrane protein crucial for maintaining the integrity of epithelial barriers in both the retina and the colon. In the retina, CRB1 plays a vital role in the structure ...

Inherited retinal degeneration (IRD) encompasses various disorders characterized by progressive loss of retinal photoreceptor cells, ultimately ...

while epithelial cells -- which compose the linings of our skin, organs and body cavities -- are mute, serving mostly as protective barriers that can absorb and secrete various substances.

"By reinforcing the gut's protective barrier, we might prevent bacteria from invading the epithelial cells that line the intestine, which could halt both the onset and progression of the disease ...

Get Instant Summarized Text (Gist) Gamma-actin plays a crucial role in the organization and mechanics of epithelial cells, particularly in cell membrane stiffness and junction dynamics. Its ...