Treatment with SBT-100 results in a decrease of activated ERK (P-ERK), a downstream effector ... Similarly, the STAT3 binding activity of SBT-100 extends to both phosphorylated STAT3 (P-STAT3 ...

Boosting MTMR7 production reversed signs of pulmonary arterial hypertension in a mouse model of PAH and may serve as a ...

"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...