[20] as well as by the distribution of cofactors and corepressors of the estrogen-receptor complex within the tissue. [21] With estradiol as the standard, binding affinity for both estrogen ...

When treating patients with hormone-receptor positive, HER2-negative metastatic breast cancer, mutations necessitate the ...

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

According to the National Cancer Institute, roughly 15% of breast cancer cases are hormone-receptor negative, in which breast cancer cells do not contain hormone (estrogen or progesterone) receptors.

[2] When studied separately from estrogen, the different progestin compounds have variable androgenic effect by their linkage with the androgenic receptor. On the other hand, progestins counter ...