Excedrin Migraine: For migraine relief, adults 18 and over should take two caplets every 24 hours. You should not take more than two caplets in 24 hours unless directed by your healthcare provider.

Do not take more than two caplets in 24 hours unless directed by a doctor. Consumers under 18 should not take Excedrin Migraine unless directed by a doctor. Excedrin Extra Strength: Adults and ...