The answer: alternative splicing. A critical finding regarding ... the CaMK IV-mediated signaling pathway leading to skipping of the STREX exon (Shin & Manley 2004, Figure 5).
Entrada Therapeutics can plough on with the development of its Duchenne muscular dystrophy (DMD) therapy, ENTR-601-44, now ...
SPLICER uses a gene editing approach called exon skipping, which is of particular interest for health conditions caused by mutations that produce misfolded or toxic proteins, such as Duchenne's ...