receptors (NMDARs) are the most important known trigger for long-term synaptic plasticity. They also show considerable mobility within the membrane and between intracellular and extracellular ...

Originally identified as a cell surface receptor that triggered the death ... and the mitogen-activated protein (MAP) kinase extracellular signal-related kinase (ERK), which led to increased ...

How these lysophospholipids worked was unclear and much debated in the decade preceding the mid-1990s, with explanations invoking lysophospholipids as membrane disruptors (lysophospholipids look a bit ...

The different positions and movements of the extracellular region appear to be an important way to activate the receptor. "This opens up new opportunities for drugging adhesion GPCRs, because now ...

In a new study, researchers from Japan found that aromatic clusters on the extracellular receptor Siglec-14 found on macrophages recognized carbon nanotubes and then mediated an immune reaction to ...

Recently, it has become clear that glycosylation as well as other posttranslational events play a crucial role in the temporal and spatial regulation of signal transmission by altering extracellular ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Thus, the basement membrane appears to be the most primordial form of extracellular matrix prerequisite for the evolution of multicellular organisms. Epithelial cells adhere to the basement membrane ...