Originally identified as a cell surface receptor that triggered the death ... and the mitogen-activated protein (MAP) kinase extracellular signal-related kinase (ERK), which led to increased ...

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

The different positions and movements of the extracellular region appear to be an important way to activate the receptor. "This opens up new opportunities for drugging adhesion GPCRs, because now ...

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

How these lysophospholipids worked was unclear and much debated in the decade preceding the mid-1990s, with explanations invoking lysophospholipids as membrane disruptors (lysophospholipids look a bit ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Thus, the basement membrane appears to be the most primordial form of extracellular matrix prerequisite for the evolution of multicellular organisms. Epithelial cells adhere to the basement membrane ...

Recently, it has become clear that glycosylation as well as other posttranslational events play a crucial role in the temporal and spatial regulation of signal transmission by altering extracellular ...