5 It was the first type of programmed cell death to be described by scientists. There are two major mechanisms for apoptosis: intrinsic apoptosis and extrinsic apoptosis. In both extrinsic and ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

Inflammatory mediators generate tissue factor expression and initiate coagulation through activation of the extrinsic pathway, while thrombin formation from activated coagulation stimulates the ...