资讯

GlobalData on MSN5 天
FDA approves J&J’s Imaavy for generalised myasthenia gravis
Johnson & Johnson's (J&J) human neonatal Fc receptor (FcRn)-blocking monoclonal antibody Imaavy (nipocalimab-aahu) has ...
Medscape6 天
FDA Approves New Monoclonal Antibody for Myasthenia Gravis
The US Food and Drug Administration has approved nipocalimab-aahu, a new FcRn- blocking monoclonal antibody, for the ...
Nature1 个月
Fcα/μ receptor mediates endocytosis of IgM-coated microbes
Here we describe a mouse Fc receptor, designated Fcα/μR, and its human homolog, that bind both IgM and IgA with intermediate or high affinity. Fcα/μR is constitutively expressed on the ...
Nature23 天
IgE in allergy and asthma today
The structural data also provide clues to the unique nature of the high-affinity IgE–FcεRI interaction, and indicate possibilities for blocking ... receptors, FcεRI (high-affinity Fc receptor ...