研究人员针对垂体肿瘤开展研究，发现 FGFR1 D129A 变异或与垂体肿瘤发生有关，意义重大。 探索垂体疾病的遗传奥秘：FGFR1 变异的关键作用 在人体内分泌系统中，垂体犹如一个 “指挥官”，它分泌的多种激素对生长、发育、代谢等生命活动起着至关重要的调节 ...

Tyra Biosciences' TYRA-300, an oral FGFR3 inhibitor, showed promising efficacy but raised concerns with some FGFR1/2-driven adverse events, causing a significant stock drop. TYRA-300 demonstrated ...

Researchers have identified in a new study that oral infigratinib, an FGFR1-3 selective tyrosine kinase inhibitor, improves ...

The activation of FGFR1 by KLX was confirmed through the observation of increased interactions between phosphorylated FGFR1 and MAP4K4, and the inhibition of this pathway by a FGFR1 inhibitor ...

The activation of FGFR1 by KLX was confirmed through the observation of increased interactions between phosphorylated FGFR1 and MAP4K4, and the inhibition of this pathway by a FGFR1 inhibitor ...