These observations led to the discovery of acetyl-CoA carboxylase (ACC) and fatty acid synthase (FAS), the two key enzymes of fatty acid synthesis. His laboratory was the first to identify these ...

Fatty-acid status during in-utero development might ... and through direct interactions with proteins. 1 The synthesis of LC-PUFA by the human placenta and fetus is limited, and therefore the ...

Hepatic synthesis ... Bile-acid-binding resins are therefore primarily used to manage hypercholesterolaemia, but the significant lipid loss they induce, including loss of fatty acids, may perhaps ...