Figure 4: Development of both the limb buds and the branchial arches is impaired in many Ptpn11-mutant chimaeras. We injected pregnant females with 3 mg/ml BrdU (600 μl) in PBS. After 1 h ...

The danger to the fetus occurs when the bands compromise limb development but they have been known to entrap the fetal trunk and head as well. Up to 70% of all amniotic bands seen on prenatal ...