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A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...
To investigate this, the team generated a mouse model in which the MTO1 gene was knocked out exclusively in hematopoietic ...
Figure 1: Liver histology of the FAH−/− mice 7 ... Cytological evidence for a relationship between normal hematopoietic colony-forming cells and cells of the lymphoid system.
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They emerge in the aorta-gonad-mesonephros region during early embryogenesis and subsequently migrate to the caudal hematopoietic tissue, which is comparable to the mammalian fetal liver.