Fibroblasts are the most common cell type in connective tissue. They can be compared to 'nature's stitches', holding together ...
The goal is to use viral vectors to induce transdifferentiation of cardiac fibroblasts and myofibroblasts into functional cardiomyocytes in situ in a patient’s heart. We are modeling and developing ...
During injury or illness, fibroblasts are activated, becoming myofibroblasts that form scar tissue by secreting collagen. When the job is done, these fibroblasts must be deactivated, or de ...