Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique that enables the detection and location of ...

(a) The basic elements of FISH are a DNA probe and a target sequence. (b) Before hybridization, the DNA probe is labeled by various means, such as nick translation, random primed labeling ...

Chromosomes occupy specific regions of a nucleus, called "chromosome territories." These subdomains might be doing much more than just keeping everything organized.

Precision Cancer Pathology group performs RNA in situ hybridization for formalin fixed paraffin embedded tissue sections, fixed cultured cells and fixed/frozen tissue sections. We use either ...

Moreover, this technique (CGH) exhibits some strengths compared to fluorescence in situ hybridization (FISH): while FISH ...