Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended. Fluorouracil interferes with the synthesis of deoxyribonucleic acid (DNA) and to a lesser ...

Data on participant characteristics including age, sex, race and skin type were abstracted ... Double-blinded; FC: 5-fluorouracil cream; RCT: Randomized controlled trial; VC: Vehicle control.

No treatment-related serious effects [25] 5.FU: 5-fluorouracil; AK: Actinic keratosis; DB: Double-blinded; FC: 5-fluorouracil cream ... individuals with fair skin color are at greater risk.