Aldosterone antagonists are the first-line diuretic therapy for moderate ... at a starting dose of 100–200 mg daily) plus furosemide (starting dose 40 mg daily). These doses must be adjusted ...

Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra-individual variation in ...

Taking into account the previously mentioned benefits, torsemide not furosemide should be the loop diuretic of choice in patients with HF. †More torsemide and bumetanide reaches the tubular ...