If your best friend is basically your family, perhaps our best birthday wishes for sisters and great messages for brothers will work best for you. No matter which way you choose to say "Happy ...

When it comes to your best friend's birthday ... but I know we'll be best friends 'til the end. Happy birthday! My life is better because you're in it. Thanks for being born!

Oprah Winfrey flew in yellow floral arrangements from Holland to make the evening extra special for her best friend Gayle King ... brought out while singing “Happy Birthday” to King was ...