G proteins are commonly used in signal transduction ... The activation is terminated by GTP hydrolysis by the GTPase domain of the α-subunit, leaving the α-subunit in the GDP-bound form and ...

Specifically, in this study, the researchers identified a 3-bp deletion in the coding region of GTPBP2, a gene that encodes a G-protein expressed in several tissues—including the canine retina. They ...