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RNF144A-VRK2-G3BP1 轴调控应激颗粒组装:癌症治疗新靶点的探索
为解决癌细胞在化疗时应激颗粒(SGs)形成机制不明的问题,研究人员开展了关于 SGs 形成调控通路的研究。结果发现 RNF144A-VRK2-G3BP1 轴参与调控 SGs 形成,抑制其可增癌细胞对化疗敏感性,为抗癌治疗提供潜在策略。 在细胞的世界里,当面临各种压力时 ...
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