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GSK-3/β-catenin 信号轴调控 ARHGAPs 影响胶质瘤细胞迁移和侵袭的研究进展
这篇综述揭示了 GSK-3/β-catenin 信号轴对 ARHGAPs 的调控,及其在胶质瘤细胞迁移和侵袭中的关键作用。 一、研究背景 癌症细胞具有改变形态和进行表型转换的能力,这一过程在恶性肿瘤的发展中起着关键作用。在恶性脑肿瘤,如胶质母细胞瘤(GBM)中,癌细胞的 ...
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