为探究心肌细胞增殖调控机制及治疗心肌梗死，研究发现 circALPK2/miR-9/GSK3B 轴可促进心肌再生 ... circALPK2 作为一种负调控因子，通过海绵机制抑制 miR-9，进而上调 GSK3β 的表达，抑制 WNT 信号通路，最终抑制心肌细胞增殖和心脏修复。敲低 circALPK2 则可打破这种 ...

Mutation of the tau-phosphorylating enzyme glycogen synthase kinase (GSK3B) has been postulated as a possible cause of dementia. Now, a US study has identified an association between a single ...