Our early studies showed how a rapidly assembled, multicellular actin cable can function as a contractile purse-string to close wounds in simple epithelia including that of vertebrate embryos, and ...

How does Ran GTPase control both protein import during interphase and spindle attachment to the chromosomes during M-phase? It all has to do with its concentration gradient in the cell.

"Since these GTPases switch between 'on' and 'off' states ... openly in the hopes that others will use them to drug their GTPase of interest, whether it's a Rab GTPase, which is implicated ...