Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These molecules do more than fuel the body—they directly influence gene expression and ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

Today, the Chan Zuckerberg Initiative (CZI) launched the Billion Cells Project, an effort to generate an unprecedented one ...

These compounds are more than just an energy source for us: they have long been suspected to indirectly affect gene function. The researchers traced how the two most common short-chain fatty acids ...

These compounds are more than just an energy source for us: They have long been suspected to indirectly affect gene function. The researchers traced how the two most common short-chain fatty acids ...

Get Instant Summarized Text (Gist) A new approach, PERISCOPE, integrates Cell Painting and Optical Pooled Screening to enable genome-scale CRISPR screens, linking cell morphology to gene function ...

The team decided to focus on how PFAS affect the gene expression of neuronal-like cells, as well as how PFAS affect lipids, which are molecules that help make up the cell membrane, among other ...

"All these functions are orthogonal," says Daniel. "They can happen independently of each other at the same time." "This level of precision for modifying DNA sequences and gene expression was not ...