A Series in The Lancet Neurology provides state-of-the-art reviews covering clinical and scientific evidence on the four most common genetic subtypes of amyotrophic lateral sclerosis (ALS), caused by ...

Explore GISTs, rare GI tumors. Discover key details on genetic causes, diagnostic methods, and cutting-edge treatment ...

and PIK3CA mutations. These tumors are known to develop via alternate genetic and epigenetic mechanisms, also known as the "serrated pathway." An alternate carcinogenesis model based on BRAF ...

Using whole-genome sequencing (WGS) data from nearly 500,000 UK Biobank participants, researchers identified a strong link ...

View Full Profile. Learn about our Editorial Policies. In their 2019 paper, Liu’s team used prime editing to alter the gene mutations causing sickle cell disease and Tay-Sachs disease. Liu explained ...

Signs of Type 5 diabetes can vary depending on the subtype but usually include: Mild to moderate elevated blood glucose ...

UD researchers extracted the DNA from the samples and worked to amplify the MDV meq oncogene, a gene essential for MDV’s ability to cause cancer, to look at its mutations. Parcells identified ...

"CRISPR has revolutionized how we think about gene editing, but it has limitations. CRISPR can't target every location in the genome, and it can't fix the thousands of mutations present in ...

They had earlier shown the same type of epigenetic changes in these genes in human pancreatic precancers termed PanINs, which are caused by a mutation in a gene called KRAS, even though there was ...

Researchers have revealed a secret behind horses' exceptional endurance – a mutation in the KEAP1 gene that boosts energy production while protecting against cellular oxidative stress.