Genome rearrangements that lead to human disorders are typically thought to be caused by mistakes that occur during recombination. A new study into the genetic basis of a CNS disorder has revealed ...

To camouflage themselves on different plants, two forms of this mimic insect bear different patterns on their backs.

Complex DNA-breakage events such as chromosomal shattering, followed by genome rearrangement, DNA repair, and end-to-end ligation, ultimately result in the formation of ecDNAs (Panel B).

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

The remaining recombinants transferred a larger amount of sequence information, but in no instances were translocations or other genome rearrangements observed. Richardson C, Jasin M. 2000 Frequent ...

Researchers show that random rearrangement of DNA determines which of seven possible mating types the ... thermophila have two nuclei: the somatic nucleus, which holds a genome that governs its own ...

New genomic analysis findings could help inform breeding efforts for apples that are tastier and more resilient. A ...

Standard clinical genetic testing with short-read whole-genome sequencing (WGS ... but in fact had a complex structural rearrangement that included both deletions and duplications of adjoining ...

Structural alterations of the genome are commonly observed in human cancer and can contribute to tumorigenesis through a variety of mechanisms including the formation of fusion oncoprotein and changes ...