Germline stem cells from the postnatal testis can convert into ES-like, multipotent germline stem cells without any genetic treatment. We will examine 1) the differences between SSCs and ES cells, 2) ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes. copies of ...

Genetic testing, via germline and somatic testing, is crucial in breast cancer to understand inherited risks and tumor behavior. Germline testing identifies hereditary mutations aiding in preventive ...

After the reported birth of CRISPRed babies in China, experts want to take time to consider the scientific, social, ethical, and philosophical consequences of editing heritable human DNA. Ashley ...

A team at Baylor College of Medicine conducted research to identify novel cell-surface cancer/germline antigens (CGAs) expressed in triple-negative breast cancer (TNBC) that could serve as targets for ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...