Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...

Traumatic brain injury, stroke, and degenerative diseases elicit complex pathogenic cascades involving glial cells such as astrocytes, microglia, and ...

N eurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste ...

Glial fibrillary acidic protein (GFAP) levels peak around 24 hours after traumatic brain injury (TBI) 2. Higher GFAP levels ...

“Typically we have concentrated on neurons for studies of dementia, as they are the cells involved in brain processing and memories. [This] study demonstrates that glia are likely to be equally ...

Glioblastoma has long resisted treatment, but scientists may have found a breakthrough by leveraging the body's own ...

In the brain, one way that neurons communicate with one another is through secretion of glutamate. Astrocytes, a type of glial cell, mop up extra glutamate, convert it to glutamine—the precursor for ...

But neurons are not alone in the brain or elsewhere in the nervous system: Brain cells called glia play various supporting roles to keep the system running smoothly. Between the axon of a ...

The Samuel lab seeks to uncover the molecular signals that facilitate communication between brain cells, paving the way for circuit repair. We use a ‘whole circuit’ approach, integrating diverse ...

Research Interests: Pain modulation systems; immune and glial regulation of neuronal function; immune-to-brain communication; glial regulation of pain, opioid analgesia, drugs of abuse, ...