In conclusion, we have shown glutamate excitotoxicity mediated by AMPA/kainate receptors to be important in CNS damage in EAE and by extrapolation, possibly in MS. Thus, AMPA/kainate antagonists ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, ...

The process is therefore self-reinforcing. Conversely, the researchers were able to significantly reduce this type of ...

Biohaven has several additional programs in development, including BHV-3500—a third-generation CGRP receptor antagonist for the prevention and acute treatment of migraine—other glutamate ...

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