研究为探究 HIV 感染者认知问题，聚焦 HIV-1 gp120 与尼古丁对小胶质细胞作用，发现其影响线粒体及淀粉样蛋白，意义重大。 《HIV-1 gp120 与尼古丁相互作用影响小胶质细胞：关乎神经炎症与认知障碍的新发现》 在全球范围内，人类免疫缺陷病毒（HIV）感染一直是 ...

When HIV is exposed to CBAs, virus escape eventually occurs predominantly by deleting its glycans on the viral envelope glycoprotein gp120. It has been shown that such mutant virus strains have an ...

福斯特马韦尔已在体外显示出能够阻止sgp120与CD4相互作用的能力，从而保护未感染的细胞免受免疫系统攻击。这表明福斯特马韦尔可能有助于减少PLWH的慢性炎症，即使他们的病毒载量无法检测到。

在多重耐药适应症方面，艾博韦泰联合3BNC117抗体作用靶点分别为HIV膜蛋白GP41和GP120，都可阻止HIV病毒进入CD4+T细胞，也可以阻断细胞介导的感染。

Preventing HIV cell entry There is no cure for AIDS ... viral strains carrying different maraviroc resistance–conferring mutations within gp120 have been observed both in cell culture ...

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...

他们观察到Nb457通过与CD4结合，诱导了CD4的D1结构域构象改变，从而有效地阻碍了HIV-1的gp120与CD4细胞的结合。同时，他们发现Nb457的表位位于MHC-II结合 ...

Determinants of HIV cell tropism & chemokine receptor usage The V3 loop of HIV-1 gp120 is a primary determinant of cell tropism and chemokine receptor usage, whereas the V1/V2 region is involved ...

The study shows that intact HIV and its viral envelope protein gp120 each cause macrophages, a type of white blood cell, to ...

They further evaluated the possible mechanisms of action in gp120-mediated HIV-1 entry and found that trilobatin did not bind to the gp120 envelope. In contrast, the positive control, HP-OVA ...