The commonly used Cockcroft-Gault method may result in excessive chemotherapy dosing — with potentially dire implications.

Tolebrutinib is an oral, brain-penetrant, and bioactive Bruton’s tyrosine kinase inhibitor that modulates peripheral inflammation and persistent immune activation within the central nervous ...

For individuals with dominantly inherited Alzheimer disease (DIAD), long-term treatment with gantenerumab may delay clinical decline.

In contrast, the highest versus the lowest intake of total plant-based oils was associated with significantly lower mortality ...

Similar elevations in risk were seen in analyses excluding people with comorbid mental or substance use disorders (hazard ratio, 3.25). Relative to the general population, people with acute care ...