Researchers use generative AI to design synthetic enhancers that can effectively control gene expression in healthy mammalian ...

Then they mapped single-cell lineage output to gene expression against a cDNA library to generate a molecular bridge database. Lu and her team used the database to quantify HSC lineage outputs across ...

In the study "Long-term lineage commitment in hematopoietic stem cell gene therapy," published in Nature, the team investigated how stem cells used in gene therapy behave differently depending on ...

Princess Margaret Cancer Center at University Health Network-led researchers constructed a detailed single-cell atlas of ...