"Gas-based therapies for disease are really ... a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity, Cell (2025). DOI: 10.1016/j.cell.2025.01.029 ...

How can a gas cause death so quickly — even ... CO blocks oxygen from attaching to hemoglobin and displaces oxygen that’s already bound because of the differences in binding affinity. Table 1. The ...

Recombinant hemoglobin in a blood substitute needs to have a lower affinity for oxygen than natural hemoglobin, as it has to function in the absence of effector molecules found inside red blood cells.

It is said that CO binds to hemoglobin in red blood cells with an affinity 200–250 times greater ... Check for leakage: If ...