Furthermore, compound 12 exhibited favorable safety profiles in single-dose toxicity and hERG inhibition tests, along with promising pharmacokinetic properties in mice. This study not only ...

A major focus of our research is on hERG channels, which are critical to normal cardiac repolarization. Inherited mutations in the hERG channel gene, or drug-induced inhibition of channel function ...

A major focus of our research is on hERG channels, which are critical to normal cardiac repolarization. Inherited mutations in the hERG channel gene, or drug-induced inhibition of channel function ...