An alternate hypothesis proposes that homologous chromosomes reside in pairs constitutively. Acting against this hypothesis is the finding that in induced recombination experiments, the broken ...

In particular, microtubules from one side of the spindle attach to one of the chromosomes in each homologous pair, while microtubules from the other side of the spindle attach to the other member ...

In summary, the novel approach proved effective and robust in the field of homologous protein search. Its ability to accurately identify remote homology pairs with distinct sequences but similar ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Mol Cell Biol. 1998;18:93-101. Johnson RD, Liu N, Jasin M. 1999 Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature. 1999;401:397-399.