These may include bleeding disorders, in which the blood doesn’t clot as well as it should, and hypercoagulable disorders, in which there is an increased tendency to form blood clots.

Common etiologies include hypercoagulable diseases, low flow states, dehydration, adjacent infectious processes, oral contraceptives, hormonal replacement therapy, pregnancy, and puerperium.

The major emphasis of the Thiagarajan Lab is to elucidate the mechanism of the hypercoagulable state associated with the presence of antiphospholipid antibodies. Patients with systemic lupus ...