Perhaps the specter of hypoglycemia is even more pertinent today... Since the introduction of insulin therapy into clinical practice in the early 1920s, hypoglycemia has been a troubling problem.

Irradiation therapy, to a total of 2850 r, was given to this mass without altering its size or reducing the frequency of the hypoglycemic episodes. The diet consisted of 3 meals a day ...

Adults with type 1 diabetes and recurrent severe hypoglycemia reduced their HbA1c to less than 7% with a full dose of VX-880. No severe adverse events associated with the therapy were reported.