Hypothalamic inflammation ... Glucose tolerance was assessed by intraperitoneal (i.p.) glucose tolerance test after 7 weeks of treatment. Mice were fasted for 6 h, and the tests were carried ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

Compared to sugar, consuming sucralose—a widely used sugar substitute—increases activity in the hypothalamus, a brain region ...

Rhythm Pharma gets orphan drug designation for its setmelanotide to treat hypothalamic obesity in Japan: Boston Friday, March 21, 2025, 16:00 Hrs [IST] Rhythm Pharmaceuticals, Inc ...

Rhythm is evaluating setmelanotide in a global Phase 3 trial in patients with acquired hypothalamic obesity, with topline data on track to be disclosed in the second quarter of 2025.

Body temperature is controlled by the hypothalamus in the brain. If the hypothalamus detects that the body is too hot, the response is that the body begins to sweat to try and reduce the ...