This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

Many people use sugar substitutes so that they can taste the sweet stuff without consuming as many calories. It's estimated ...

Compared to sugar, consuming sucralose—a widely used sugar substitute—increases activity in the hypothalamus, a brain region that regulates appetite and body weight, according to new USC research.

Hypothalamic inflammation ... Glucose tolerance was assessed by intraperitoneal (i.p.) glucose tolerance test after 7 weeks of treatment. Mice were fasted for 6 h, and the tests were carried ...

Rhythm is evaluating setmelanotide in a global Phase 3 trial in patients with acquired hypothalamic obesity, with topline data on track to be disclosed in the second quarter of 2025.