The mechanisms behind this sex-related difference are unknown. The damage associated with prematurity can be mimicked in rodents by prolonged exposure to sublethal postnatal hypoxia. This chronic ...

Tumour hypoxia has been pursued as a cancer drug target for over 30 years, most notably using bioreductive (hypoxia-activated) prodrugs that target antineoplastic agents to low-oxygen tumour ...

The aims of the present review are therefore threefold: first, to summarise the main mechanisms for interval training and repeated sprint training in normoxia. Second, to critically analyse the ...

Chemically restoring intestinal gut hypoxia could deter fungal blooms. Sahana is a science journalist and an ... On digging into this issue, Bays discovered that what seemed like a case of resistant ...

"However, it has been unknown, under hypoxia, whether and how HIF1α regulates ... function in T cells is a major T cell-intrinsic mechanism of therapeutic resistance to ICBs, like anti-CTLA ...

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by ...

Kenneth Eugene Smith, an inmate in the US State of Alabama, Thursday became the first person ever to be put to death through the controversial nitrogen hypoxia mechanism. “Tonight Alabama caused ...

Researchers at the University of Virginia have discovered a new mechanism driving drug resistance ... Unveiling the role of hypoxia in pancreatic cancer progression Pancreatic tumors are notorious ...

Simultaneously, chronic intermittent hypoxia (CIH) in OSA patients induces metabolic disturbances, fostering the development of MetS. Understanding these mechanisms is essential for devising ...

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered, potentially paving the way for innovative treatments that align with the natural ...

To explore the underlying mechanisms, the team performed single ... treatment with the identified placenta-derived factor under hypoxia is a crucial human liver organoid culture technique that ...