The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by ...

It seems that proteins called hypoxia-inducible factors (HIFs) can affect gene expression in low-oxygen conditions. While some control of gene expression is mediated through control of whether a ...

Previously, it has been suggested that hypoxia-inducible factor (HIF) 1 signaling may play determinative role in the maintenance of the barrier function of the intestinal epithelium in ...

In short, this study shows that poor sleep and poor diet can create the perfect storm for developing diabetes—not because you ...

HIF1α is a subunit of HIF, or hypoxia-inducible factor, that is known to play a crucial role in orchestrating cellular responses to hypoxia. Shi and colleagues showed this key role for HIF1α in ...

It focuses on the hypoxia-inducible factor and connective tissue growth factor biology to develop medicines for the treatment of anemia, fibrotic disease, and cancer. The company was founded by ...

Van Meir has developed novel therapeutic approaches for cancer using oncolytic adenoviruses and anti-angiogenic molecules and is currently developing novel small molecule inhibitors of the ...

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered, potentially paving the way for innovative treatments that align with the natural ...