A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell ...

or novel targeted therapies (JAK1–2 inhibitors or histone deacetylase inhibitors). Minimal residual disease/operational cure or cure is foreseen in patients with ET and PV if treatment with IFN ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...

For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...