Hosted on MSN1mon
Safeguarding intestinal stem cells during aging through balanced signaling
A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...
News Medical2y
IFN-γ: A therapeutic target for cancer therapy
Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...
Medscape6d
A New Era for IFN-α in the Treatment of Philadelphia-negative Chronic Myeloproliferative Neoplasms
IFN-α2 (in most centers today pegylated IFN-α2 [Peg-IFN-α2]) induces major or complete molecular remissions in a subset of JAK2V617-positive patients with essential thrombocythemia (ET) and ...
Nature7mon
Knocking the SOCS off a tumor suppressor
The STAT family has six members (STAT1–6), each of which transduces the signal of particular cytokines. For instance, signaling from the interferon (IFN) receptors, interleukin-4 (IL-4 ...