These additional data suggest that IgAD that does not progress to CVID may not be associated with TACI sequence variants.

Common variable immunodeficiency (CVID) is a primary immunological disease with variable severity, ranging from mild forms of infections to chronic progressive complications. The hallmark of this ...

We are currently examining the functional effects of the heterozygous TACI variants to better understand the mechanism by which these variants contribute to the development of CVID. Note ...

However, in individuals with a specific type of immunodeficiency, immunoglobulin A (IgA) deficiency, the immune system does ...

These products differ in a number of ways, including the Ig concentration, IgG subclass distribution, residual content of IgA, approved maximum ... may also improve CVID-associated granulomatous ...