The deal with startup Dren Bio hands Sanofi a so-called myeloid cell engager that would compete with an array of programs ...

T cells, move over. B cells are now reported ... even antigen-naïve animals often express “natural antibodies”. These are immunoglobulin M (IgM) and, less commonly, IgG or IgA; they bind ...

When this method was applied to WGS data it revealed that B cells producing IgM/D antibodies in the blood (produced when the body first encounters a foreign antigen) were the only type of B cell ...

which is a CD20 x CD3 bispecific IgM antibody designed to treat patients with B cell Non-Hodgkin's lymphoma and other B cell malignancies, IGM-8444, which is an IgM antibody targeting Death ...

In February of 2000, she told me that B cells from patients with hyper-IgM syndrome type 2 tested at the Necker Hospital seemed to have defects in SHM. However, I was not convinced, because our ...

The work focuses on the interaction of B cells and T cells in the body's immune ... in an immune deficiency disease called X-linked Hyper IgM syndrome, or X-HIgM. It's a genetic disorder affecting ...