One of the genetic causes of CeH is mutations in the immunoglobulin superfamily member 1 (IGSF1) gene. IGSF1 deficiency syndrome is associated with various clinical features, including growth ...

"The antigen Izumo is a novel protein of the immunoglobulin superfamily," Okabe, the senior author of the study, told The Scientist. Proteins belonging to this family are membrane-anchored, and are ...

In addition to heparin/heparan sulfates, HMGB1 binds to the immunoglobulin superfamily protein RAGE (receptor for advanced glycation end-products), which mediates the neurite outgrowth-promoting ...

More information: Jiro Osaka et al, Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity, Cell Reports (2024). DOI: 10.1016/j.celrep.2024. ...

Each cytokine acts through its own receptor on target cells, and these receptors include members of the immunoglobulin (Ig) superfamily and tumour necrosis factor (TNF). Cell-type-specific SARS ...