Researchers have discovered that a common amino acid found in most meats, dairy and nuts could be a cause of arthritis ...

Their findings, published in Nature Communications, offer new insights for dietary-based cancer treatments and highlight the critical role of the tryptophan metabolite indole 3-pyruvate (I3P ...

Phosphoribosylanthranilate isomerase (PRAI) and indole-3-glycerol phosphate synthase (IGPS) are distantly related α/β-barrel enzymes that catalyze successive steps in tryptophan biosynthesis.

In an article published in Cell Reports, Nagler’s team demonstrated that Clostridia-produced flagella and indole, a tryptophan metabolite, also promote barrier integrity. 3 To determine the role of ...