Conditional gene targeting based on excision or inversion ... construct and the loxP-flanked target sequences. In the case of inducible systems, one must also examine recombination before and ...

However, we have a group of ‘essential genes’ that we cannot remove because it results in cell death.” To overcome this, Adli and colleagues utilize reversible auxin-inducible degron (AID) tools that ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival. Amid cuts to federal funding, US universities tighten budgets, ...

Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector nucleases (TALENs) gene editing to overcome these shortcomings by making CAR T ...

New Rochelle, NY, February 19, 2025—A new study in the peer-reviewed Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I (RIG-I) agonist RNA ...

A new study in the Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I (RIG-I) agonist RNA (RAR) induces innate immune signaling and death of ...