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《Cell》杂志刊登了一项来自以色列魏茨曼科学研究所Rotem Sorek教授团队,联合哈佛医学院、Dana-Farber癌症研究中心的科学家的研究,该研究构建了一套基于结构预测的筛选系统,成功从3000多万个噬菌体蛋白中识别出能“瘫痪免疫系统”的武器级分子。 病毒与宿主的斗争从未停止,而噬菌体(感染细菌的病毒)是最古老、最丰富的病毒类型。研究者借助AlphaFold2-Multimer结构预测工 ...
Researchers have used spatial Deep Visual Proteomics workflow to reveal why some patients with the hereditary disease remain ...
A laboratory on Long Island has found a breakthrough in the fight against pancreatic cancer that can “intercept” its spread.
Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced ...
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...
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News-Medical.Net on MSNTraditional Chinese medicine targets cholesterol metabolism for cancer treatmentResearchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat cancer.
"The screen checks the activity of the inhibitor in a real cell environment which includes proteases and other proteins that can sometimes interfere with peptide activity, while also checking ...
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